Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression
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چکیده
منابع مشابه
Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression.
High levels of plasma adiponectin are associated with low levels of inflammatory markers and cardioprotection. The mechanism via which adiponectin exerts its anti-inflammatory effect is yet unknown. In the present study, we demonstrate that globular adiponectin (gAd) induces the expression of the inactive isoform of IL-1R-associated kinases (IRAK), IRAK-M. Homologous deletion of IRAK-M in IRAK-...
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Print ISSN: 0022-1767 Online ISSN: 1550-6606. Immunologists, Inc. All rights reserved. Copyright © 2015 by The American Association of 9650 Rockville Pike, Bethesda, MD 20814-3994. The American Association of Immunologists, Inc., is published twice each month by The Journal of Immunology at Shnghai Iform aion C eter or L fe Scnces, C A S on D ecem er 9, 2015 hp://w w w jim m unl.org/ D ow nlade...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2009
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.0803694